EPFL Team Releases BindCraft AI System for Protein Binder Design with 10-100% Success Rate Without High-Throughput Screening

EPFL Team Releases BindCraft AI System for Protein Binder Design with 10-100% Success Rate Without High-Throughput Screening

Exclusive compilation, unauthorized use will be pursued. Protein-protein interactions are at the core of all biological processes. Traditional protein binder design relies on methods such as immunization, antibody library screening, or directed evolution, which are often time-consuming and have a low success rate. Recently, the team led by Bruno E. Correia at the École Polytechnique … Read more

BindCraft: A One-Shot Protein Design Tool for Functional Protein Binders (Nature 2025)

BindCraft: A One-Shot Protein Design Tool for Functional Protein Binders (Nature 2025)

BindCraft is a new computational tool designed for the one-shot method of creating functional protein binders. https://www.nature.com/articles/s41586-025-09429-6 Here are some key points from the paper: [Apologies for the long delay in updates] What is BindCraft? BindCraft is an open-source, automated one-stop protein binder design process aimed at simplifying the de novo design of protein binders. … Read more