Progression-Free Survival Increased Fivefold, Intracranial Response Rate at 65.7%! ‘Miraculous Anti-Cancer Drug’ Solves the Treatment Challenge of Breast Cancer Brain Metastases

Progression-Free Survival Increased Fivefold, Intracranial Response Rate at 65.7%! 'Miraculous Anti-Cancer Drug' Solves the Treatment Challenge of Breast Cancer Brain Metastases

What else can DS-8201 not do? Recently, the “miraculous anti-cancer drug” DS-8201 announced data from its DESTINY-Breast03 trial involving patients with brain metastases[1]: Among 43 patients with HER2-positive breast cancer brain metastases treated with DS-8201, the median progression-free survival reached 15.0 months, with intracranial objective response rate and overall objective response rate at 65.7% and … Read more

Laser and Gold Nanoparticles: Breaking the Blood-Brain Barrier for Faster Drug Delivery

Laser and Gold Nanoparticles: Breaking the Blood-Brain Barrier for Faster Drug Delivery

Written by | Xiao Xia Edited by | Wang Duoyu Formatted by | Shui Chengwen Blood-Brain Barrier (BBB) is the barrier formed between the plasma and brain cells by the walls of brain capillaries and glial cells, and the barrier formed between plasma and cerebrospinal fluid by the choroid plexus, only allowing specific types of … Read more

Cationic Magnetic Nanoparticles Enhance NK Cell Activity in GBM

Cationic Magnetic Nanoparticles Enhance NK Cell Activity in GBM

iNature Glioblastoma (GBM) has an immune-suppressive microenvironment and blood-brain barrier (BBB) that severely hinders the infiltration and activity of natural killer (NK) cells, thereby reducing their clinical efficacy in GBM treatment. On December 23, 2024, Zhang Xianzheng from Wuhan University published a study titled “Cationic Magnetic Nanoparticles Activate Natural Killer Cells for the Treatment of … Read more