Probiotics

Literature Sharing | J AM CHEM SOC | Probiotic-Drug Conjugates Achieve Site-Specific Probiotic Colonization and On-Demand Drug Release to Combat Ulcerative Colitis and Its Complications

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Literature Sharing | J AM CHEM SOC | Probiotic-Drug Conjugates Achieve Site-Specific Probiotic Colonization and On-Demand Drug Release to Combat Ulcerative Colitis and Its Complications

1. Research Background Ulcerative colitis (UC) is a chronic intestinal disease that severely affects the quality of life of patients and significantly increases the risk of colorectal cancer (CAC) associated with colitis, posing a major threat to patient survival. Current treatment strategies for UC are limited by single therapeutic mechanisms, uncontrolled drug release, and non-specific … Read more

How Does Vitamin C Supplementation Affect Your Gut Microbiome?

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How Does Vitamin C Supplementation Affect Your Gut Microbiome?

Friends who have experience with high doses of vitamin C may have noticed a phenomenon: When increasing the dosage for the first time, gas production in the gut seems to increase, but as the body adapts, this situation returns to normal. Have you ever thought that this subtle change might indicate that vitamin C plays … Read more

Triple-Functional Probiotics with Intracellularly Synthesized Selenium Nanoparticles for Colitis Therapy by Regulating the Macrophage Phenotype and Modulating Gut Microbiota

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Triple-Functional Probiotics with Intracellularly Synthesized Selenium Nanoparticles for Colitis Therapy by Regulating the Macrophage Phenotype and Modulating Gut Microbiota

Click the blue text to follow us!Abstract Macrophage phenotype dysregulation is a major cause of colitis, as it not only enhances oxidative stress and exacerbates inflammatory responses but is also closely related to dysbiosis of the gut microbiota. To effectively treat colitis, it is necessary to address these three issues simultaneously, but current treatments are … Read more