systemic functional linguistics

DANAMI 3-PRIMULTI Substudy – Complete Revascularization Guided by FFR Improves Prognosis in STEMI Patients with Severe Nonculprit Lesions

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DANAMI 3-PRIMULTI Substudy - Complete Revascularization Guided by FFR Improves Prognosis in STEMI Patients with Severe Nonculprit Lesions

Research Background In patients with ST-segment elevation myocardial infarction (STEMI), approximately 50% have multivessel disease (MVD), which is associated with a poor prognosis, especially when there are three-vessel lesions or chronic total occlusions. Although emergency PCI is the standard treatment for STEMI, there is still controversy regarding the management strategy for nonculprit lesions (complete revascularization … Read more

Subgroup Analysis of DANAMI-3-PRIMULTI: The Impact of Age on Prognosis After Complete Revascularization

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Subgroup Analysis of DANAMI-3-PRIMULTI: The Impact of Age on Prognosis After Complete Revascularization

Research Background With the increasing number of elderly patients receiving primary percutaneous coronary intervention (PPCI), the management strategies for non-culprit lesions have become controversial. Although multiple studies support that complete revascularization (treating all significant stenosed vessels) can improve prognosis, the benefits for elderly patients (≥75 years) remain unclear due to their comorbidities and shorter life … Read more

DANAMI-3-PRIMULTI Substudy—Cardiac Magnetic Resonance Confirms the Impact on Cardiac Structure and Function

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DANAMI-3-PRIMULTI Substudy—Cardiac Magnetic Resonance Confirms the Impact on Cardiac Structure and Function

Research Background Patients with ST-segment elevation myocardial infarction (STEMI) combined with multivessel disease (MVD) account for approximately 45% of all STEMI patients, and they have a poorer clinical prognosis. Previous studies (such as PRAMI, CvLPRIT) have shown that complete revascularization (treating all significantly narrowed vessels) can reduce major adverse cardiovascular events (MACE) compared to treating … Read more

Analysis of Lesion Characteristics in the DANAMI-3-PRIMULTI Substudy

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Analysis of Lesion Characteristics in the DANAMI-3-PRIMULTI Substudy

Research Background and Objectives The DANAMI-3-PRIMULTI trial has confirmed that in patients with ST-segment elevation myocardial infarction (STEMI) and multivessel disease (MVD), fractional flow reserve (FFR)-guided complete revascularization (FFR-CRV) can significantly reduce the need for subsequent ischemia-driven revascularization (ID-RV), but it has no significant impact on mortality or reinfarction. The core questions of this substudy: … Read more

Analysis of Bleeding Events in the DANAMI-3-PRIMULTI Substudy

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Analysis of Bleeding Events in the DANAMI-3-PRIMULTI Substudy

Research Background and Objectives In patients with ST-segment elevation myocardial infarction (STEMI) and multivessel disease (MVD), the strategy of complete revascularization (CRV) can reduce ischemic events, but its impact on bleeding risk remains unclear. Core Questions: – Does staged complete revascularization (FFR-guided) during hospitalization increase the risk of severe bleeding? – What is the impact … Read more

Research on Multimodality in the Field of Linguistics in China

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Research on Multimodality in the Field of Linguistics in China

The research on multimodality in the field of linguistics in China has formed a research pattern centered on systemic functional linguistics since its introduction in the early 21st century, integrating multiple disciplines. The following is a comprehensive overview from the perspectives of development context, theoretical framework, core areas, research hotspots, and challenges: 1. Development Context … Read more