Recent Advances in Analytical Methods for Antibody-Drug Conjugates (ADCs): From In Vitro to In Vivo (Part 2)

Recent Advances in Analytical Methods for Antibody-Drug Conjugates (ADCs): From In Vitro to In Vivo (Part 2)

Good article to read: Abstract: In the past decade, antibody-drug conjugates (ADCs) have sparked a new wave of development in the biopharmaceutical market due to their high efficacy in cancer treatment. As of now, the U.S. Food and Drug Administration (FDA) has approved 13 types of ADCs for clinical treatment. The development of ADCs relies … Read more

In-Depth Analysis of PCB Equivalent Thermal Conductivity Calculation Methods in FLOEDA Bridge

PCBs are composed of high thermal conductivity copper and low thermal conductivity dielectric materials stacked alternately, exhibiting significant anisotropy. Simcenter FLOEDA Bridge simplifies complex layered structures into homogeneous blocks with equivalent thermal conductivity, greatly enhancing the efficiency of system-level thermal analysis. This article will delve into the two core methods used by FLOEDA for calculating … Read more

Compilation of Chemistry Exam Questions from Chongqing: Topic 10 – Transformation of Substances and Process Flow

Compilation of Chemistry Exam Questions from Chongqing: Topic 10 - Transformation of Substances and Process Flow

Topic10 Transformation of Substances and Process Flow Knowledge Points Covered Chemistry of Elements:Se、Ru、Fe、Sn、Cr and other elements’ valence, electron configuration, and compound properties. Reaction Principles: oxidation-reduction reactions, coordination reactions, hydrolysis reactions, and precipitation-dissolution equilibrium. Experimental Operations: titration analysis, precipitation separation, pyrolysis, condensation,pH control, etc. Calculation Skills: mass fraction, concentration calculations,Ksp applications, titration calculations, etc. Information Extraction: … Read more

Development of Analytical Methods for ADC Drugs

Development of Analytical Methods for ADC Drugs

Antibody-drug conjugates (ADC) mainly consist of three “modules”: an antibody (generally a monoclonal antibody), a linker, and a cytotoxic drug (Payload). In recent years, ADC drugs have stood out among biopharmaceuticals due to their combination of the potent killing effect of chemotherapy drugs and the precise targeting of antibody drugs, earning them the title of … Read more

How to Detect Vitamin C in Products

How to Detect Vitamin C in Products

Since when has Vitamin C become a “miracle drug”? Many people, upon showing symptoms of a cold, hurry to drink a large glass of orange juice or take various Vitamin C supplements in hopes of completely driving away the pathogens. So, is Vitamin C really the “miracle drug” for colds? We need to start with … Read more