Analysis Method Development for ADC Drugs

Antibody-drug conjugates (ADCs) are primarily composed of three “modules”: an antibody (usually a monoclonal antibody), a linker, and a cytotoxic drug (payload). In recent years, ADCs have stood out among biological drugs due to their combination of the potent killing effect of chemotherapy agents and the precise targeting of antibody drugs, earning the title of … Read more

High-Throughput Industrial Preparation Chromatography Systems and DAC Columns in Pharmaceutical Applications

High-Throughput Industrial Preparation Chromatography Systems and DAC Columns in Pharmaceutical Applications

Globally, the pharmaceutical industry has formed a relatively stable pattern, dominated by well-known pharmaceutical giants such as Pfizer, Johnson & Johnson, Novartis, and Bayer, while emerging biotechnology companies are gaining market share through innovation. The market size of the pharmaceutical industry in China is also continuously growing, with total drug sales reaching 1.7 trillion yuan … Read more

Introduction to NoC Bus Architecture Topology

Introduction to NoC Bus Architecture Topology

Once you understand the memory access path, you might wonder: what exactly are the read and write requests sent out by the processor? To clarify this, we need to introduce the bus. Below, I will discuss the ARM’s AXI/ACE bus protocols and the bus structures derived from them. These two protocols are widely used in … Read more

Development of Analytical Methods for ADC Drugs

Development of Analytical Methods for ADC Drugs

Antibody-drug conjugates (ADC) mainly consist of three “modules”: an antibody (generally a monoclonal antibody), a linker, and a cytotoxic drug (Payload). In recent years, ADC drugs have stood out among biopharmaceuticals due to their combination of the potent killing effect of chemotherapy drugs and the precise targeting of antibody drugs, earning them the title of … Read more

Principles of POCT Technology | Chemiluminescence, Biosensors, Microfluidics, Immunochromatography…

Principles of POCT Technology | Chemiluminescence, Biosensors, Microfluidics, Immunochromatography...

01 Dry Chemical Analysis Technology Dry chemical technology is compared to traditional wet chemical technology, where the liquid present in the sample serves as the reaction medium. The components to be measured react directly with dry reagents fixed on a carrier, allowing for qualitative observation or instrument detection (semi-quantitative) for chemical analysis. Single-layer Test Paper … Read more

Creating High-Performance SoCs Using NoC Technology

Creating High-Performance SoCs Using NoC Technology

Years ago, a system-on-chip (SoC) with one million transistors was considered a large device, but today, SoCs with up to one billion transistors are common. Driven by Moore’s Law and the continuous reduction in process sizes, to further meet the performance requirements of applications, the integration of SoC chips has become increasingly high, and system … Read more

Complex Design Choices for System-on-Chip (SoC): Cores, IP, EDA, and NoC

Complex Design Choices for System-on-Chip (SoC): Cores, IP, EDA, and NoC

System-on-Chip (SoC) is an integrated circuit that integrates a computing processor and other electronic systems into a single chip. SoCs can handle digital signals, analog signals, mixed signals, and even radio frequency signals, and are often used in embedded systems. Although microcontrollers (MCUs) typically have less than 100 kB of RAM, they are essentially a … Read more

SoC Design: When Network-On-Chip Meets Cache Coherency

SoC Design: When Network-On-Chip Meets Cache Coherency

Many people have heard of the term cache coherency, but do not fully understand the considerations for System-on-Chip (SoC) devices, especially those using Network-on-Chip (NoC). To understand the current issues, one must first grasp the role of cache in the memory hierarchy. Cache in Memory Hierarchy The CPU has relatively few extremely fast registers. The … Read more

3D Film-Like Nanozyme for Ultrasensitive Detection of Respiratory Viruses

3D Film-Like Nanozyme for Ultrasensitive Detection of Respiratory Viruses

Respiratory viral infections pose a significant challenge to global public health, and rapid and accurate detection is crucial for timely diagnosis and treatment. Traditional detection methods such as ELISA and PCR have limitations including complex operations and long processing times. Lateral flow immunoassay (LFA) test strips have become an ideal instant detection technology due to … Read more