Introduction: Behind the Disappearance of Memory: How Will You Accompany Your Mother? Have you ever had moments like this? Your originally gentle and determined mother suddenly puts her keys in the refrigerator or carelessly piles the washed clothes on the coffee table. You go from initial jokes and teasing to an increasingly heavy sense of … Read more
1. Mol Psychiatry | Synaptic Vulnerability to β-Amyloid and Tau Pathologies Differentially Disrupts Emotional and Memory Neural Circuits Research Background: The core symptoms of Alzheimer’s Disease (AD) include memory loss and neuropsychiatric abnormalities (such as anxiety), with pathological markers being amyloid beta (Aβ) plaques and tau neurofibrillary tangles in the brain. However, how Aβ and … Read more
18F-FDG PET Reveals the Truth Behind Alzheimer’s Disease in Patients with Memory Impairment Currently, the diagnosis of Alzheimer’s Disease (AD) still faces many challenges, especially in patients initially diagnosed with memory impairment, where accurately distinguishing AD from other types of dementia is particularly important. In recent years, 18F-FDG PET, as an advanced molecular imaging technology, … Read more
Professor Xu Haibo’s team from the Department of Radiology at Zhongnan Hospital of Wuhan University recently published a paper titled “Lifespan trajectories of fornix volume and tractography: a 5.0 T MRI study” in the renowned neuroscience journal Cerebral Cortex. In 1937, neuroanatomist James Papez proposed a closed neural circuit composed of the hippocampus, mammillary bodies, … Read more
1 Introduction This introduction discusses the pathological complexity of Alzheimer’s Disease (AD) and the limitations of traditional research methods, gradually leading to the technical innovations and scientific significance of the study. 1.1 Disease Background and Clinical Needs • Epidemiological Data: AD accounts for 60%-70% of global dementia cases, with an estimated 152 million patients by … Read more
Written by︱Dan Xiaocai, Cao Jun, Zhao Yifan Editor︱Wang Sizhen Edited by︱Yang Binwei Alzheimer’s disease (Alzheimer’s disease, AD) is the most common form of dementia, leading to memory loss and cognitive impairment. According to the World Health Organization, over 55 million people are currently diagnosed with some form of dementia[1, 2]. The increasing global aging population … Read more
WeChat public platform followed by tens of thousands of nuclear medicine professionals 18F-FDG PET Reveals the Truth Behind Alzheimer’s Disease in Patients with Memory Impairment Currently, the diagnosis of Alzheimer’s Disease (AD) still faces many challenges, especially in patients initially diagnosed with memory impairment, where accurately distinguishing AD from other types of dementia is particularly … Read more