Proteomics

Base-Induced N-Terminal Peptide Sequencing Method

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Base-Induced N-Terminal Peptide Sequencing Method

Hello everyone, today I would like to share an article published in JACS: After 75 Years, an Alternative to Edman Degradation: A Mechanistic and Efficiency Study of a Base-Induced Method for N‑Terminal Peptide Sequencing. The corresponding authors are Professors Eric V. Anslyn and Edward M. Marcotte from the University of Texas at Austin. Professor Anslyn’s … Read more

Breakthrough in Alzheimer’s Disease Research! MR-SPI Crushes IVW with ‘Voting Rules’

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Breakthrough in Alzheimer's Disease Research! MR-SPI Crushes IVW with 'Voting Rules'

1 Introduction This introduction discusses the pathological complexity of Alzheimer’s Disease (AD) and the limitations of traditional research methods, gradually leading to the technical innovations and scientific significance of the study. 1.1 Disease Background and Clinical Needs • Epidemiological Data: AD accounts for 60%-70% of global dementia cases, with an estimated 152 million patients by … Read more