alkyl boronic esters

Vicinal Stereocenter Construction via α-Boryl Carbanions from Borylated Cyclopropanes

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Vicinal Stereocenter Construction via α-Boryl Carbanions from Borylated Cyclopropanes

The Technion – Israel Institute of Technology Professor Ilan Marek’s team utilized α-boryl carbanion intermediates as a platform for stereochemical generation, exploring the complex behavior of α-boryl carbanions generated from various cyclopropyl boronic methyl iodides in selective ring-opening and electrophilic reactions, conducting a series of highly stereoselective nucleophilic substitution reactions to construct vicinal stereocenters. Abstract … Read more

Polycyclic Scaffolds through the Intermediacy of Boron-Stabilized Nonclassical Carbocations

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Polycyclic Scaffolds through the Intermediacy of Boron-Stabilized Nonclassical Carbocations

Boston CollegeProfessor James P. Morken’s team has demonstrated that in the presence of catalytic amounts of Brønsted acid, boron-containing norbornene derivatives undergo regioselective rearrangement to generate boron-containing nortricyclanes. The selective functionalization of boronic esters allows for the acquisition of various multisubstituted tricyclic structures, providing opportunities for broader applications. Abstract In the presence of catalytic amounts … Read more

Photocatalytic N-Alkylation

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Photocatalytic N-Alkylation

From J. Am. Chem. Soc. Hi, everyone! Do you remember the article we shared recently about the activation of alkyl boronic esters by morpholine radicals in the “perfectly flawless” Quasi-Suzuki Coupling? The morpholine radical couples with alkyl boronic esters to generate alkyl radicals and aryl halides. So, can the radicals produced by this pathway be … Read more