Direct Activation of Sulfides by C–H Oxidation with Photoexcited Nitroarenes: Formal Manipulations of the C─S Bond

Direct Activation of Sulfides by C–H Oxidation with Photoexcited Nitroarenes: Formal Manipulations of the C─S Bond

——Green Pharmaceutical Team—— Starfish Review 【Background】The thioether group is widely present in functional materials, drug molecules (such as Montelukast and Diltiazem), and ligand design, but its chemical inertness limits its synthetic applications. Traditional activation of sulfides relies on direct oxidation of sulfur atoms (to form sulfoxides/sulfones), facing bottlenecks such as poor chemical selectivity (prone to … Read more

Photocatalytic N-Alkylation

Photocatalytic N-Alkylation

From J. Am. Chem. Soc. Hi, everyone! Do you remember the article we shared recently about the activation of alkyl boronic esters by morpholine radicals in the “perfectly flawless” Quasi-Suzuki Coupling? The morpholine radical couples with alkyl boronic esters to generate alkyl radicals and aryl halides. So, can the radicals produced by this pathway be … Read more