N-Alkylation

Photocatalytic N-Alkylation

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Photocatalytic N-Alkylation

From J. Am. Chem. Soc. Hi, everyone! Do you remember the article we shared recently about the activation of alkyl boronic esters by morpholine radicals in the “perfectly flawless” Quasi-Suzuki Coupling? The morpholine radical couples with alkyl boronic esters to generate alkyl radicals and aryl halides. So, can the radicals produced by this pathway be … Read more

Goodbye Morpholine Radical

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Goodbye Morpholine Radical

From J. Am. Chem. Soc. Hi, everyone! I wonder if you still remember that I shared an article titled 【J. Am. Chem. Soc.】Me₃N•BH₃—— Cu Catalyzed Halogenated Alkane + Primary Amide N-Alkylation, which achieved amide N-alkylation by generating alkyl radicals through XAT halogen transfer. However, in an earlier discussion, we learned that the 【J. Am. Chem. … Read more