pH-Activated Nanoplatform for Tumor Therapy

Professor Yu Zhiqiang from Southern Medical University and Researcher Tang Longguang from Zhejiang University published a research paper titled “pH-activated nanoplatform for visualized photodynamic and ferroptosis synergistic therapy of tumors” in the international academic journal Journal of Controlled Release (IF=11.467). Compared to traditional chemotherapy, photodynamic therapy (PDT) can effectively reduce side effects and prevent drug … Read more

4Pi-SIM Imaging Technology for Live Cell 3D Resolution

Subcellular organelles in cells often have intricate three-dimensional structures and biological functions. Observing the three-dimensional distribution and dynamics of organelles using fluorescence microscopy helps understand cellular functions and reveals interactions between organelles. However, fluorescence microscopy is limited by optical diffraction and the numerical aperture (NA) of the objective lens, resulting in blurred low-resolution images. Due … Read more

Cascaded Nano-Reactor Enhances Sonodynamic Therapy for Colon Cancer

Sonodynamic Therapy (SDT) is a novel non-invasive tumor treatment method that utilizes ultrasound to activate sonosensitizers to generate reactive oxygen species (ROS) to induce tumor cell death. Based on the deep tissue penetration capability of ultrasound, SDT can treat deep tumors and has broad clinical transformation prospects. The main mechanism of SDT is the generation … Read more

Transforming Cancer-Associated Fibroblast Barriers for Tumor Treatment

The cancer-associated fibroblast (CAF) barrier in pancreatic ductal adenocarcinoma (PDAC) significantly restricts clinical prognosis. The main obstacles in PDAC treatment include limited immune cell and drug penetration, as well as an immunosuppressive microenvironment. Based on this, Yongjun Liu and Na Zhang from Shandong University reported a “shooting fish in a barrel” strategy by preparing a … Read more

PyQt5 Example: Raspberry Pi + MPU6050 Data Collection

Click the above“Mechanical and Electronic Engineering Technology” to follow us System Configuration: Raspberry Pi 3B+, Operating System Raspbian-stretch, Python version is python3.5.3 Functional Requirements: Design a QT interface to collect data, with a start collection button that begins data collection when clicked, and a stop button that stops data collection when clicked. The data should … Read more

Oxygen Vacancy Piezoelectric Nanosheets for Ultrasound Tumor Therapy

Piezoelectric Dynamic Therapy (PzDT) is a tumor treatment method that utilizes mechanical energy to trigger the polarization of piezoelectric materials. Under the action of ultrasound (US), the immense pressure generated by the collapse of cavitation bubbles serves as a mechanical force source for the piezoelectric sonosensitizer, showing feasible potential. An internal electric field can form … Read more

In Situ Electron Microscopy Study of Dynamic Structural Changes in CuZn Bimetallic Nanoparticles

Background Introduction Bimetallic nanocomposites have gained widespread attention due to their tunable physicochemical properties and significant applications in engineering and catalysis. In nanocomposites, the synergistic effects between metal elements often lead to excellent catalytic performance, even imparting unique properties that are not present in single metal elements. However, bimetallic alloys face issues of structural and … Read more

Multicomponent Herbal Small Molecule Hydrogels for TBI Treatment

iNature Self-assembling hydrogels for mechanical support and drug delivery have been widely studied in the context of traumatic brain injury (TBI). However, most self-assembling hydrogels rely on polymer carriers or the introduction of exogenous inactive substances, often raising biosafety concerns and making clinical translation difficult. On October 9, 2024, a research paper titled “Small Molecule … Read more

Cold Exposure Therapy Enhances Breast Cancer Treatment

iNature Cold exposure therapy (CE) is a low-cost, non-invasive treatment for malignant tumors. When the body is exposed to a cold environment, it activates the thermogenic metabolism of brown adipose tissue (BAT), quickly inducing tumor starvation and inhibiting tumor growth. The microenvironmental changes caused by CE can further complement conventional treatments (such as radiotherapy and … Read more

Building a Portable PyPI Server with Raspberry Pi

In this article, I will discuss how to clone the PyPI repository onto a Raspberry Pi and provide content so that connected devices can install dependencies using the <span>pip install</span> command without an internet connection. Objective There are many ways to create your own PyPI mirror, and my method may be suitable for everyone now. … Read more