How to Apply ADC Coupling Strategies to Antibody-Conjugated LNPs?
The success of ADCs (Antibody-Drug Conjugates) relies on the continuous evolution of three generations of coupling technologies. From the “coarse” non-specific coupling to the “precise” gene-engineered modifications, and then to the “efficient” natural antibody modifications. Today, this iterative logic is providing key insights for breakthroughs in targeted delivery of antibody-conjugated LNPs (Ab-LNP).Ab-LNP requires precise coupling … Read more
