New Strategies for Cancer Treatment Using Copper Ions: Insights from Cuproptosis
Cuproptosis is a novel copper-dependent programmed cell death mechanism, which centers on the interaction between copper ions and acylated proteins in the tricarboxylic acid (TCA) cycle, leading to protein aggregation and mitochondrial dysfunction, ultimately resulting in cell death. This mechanism provides new insights for cancer treatment, as the accumulation of copper ions in tumor cells … Read more