Liver Failure

Mechanisms and Prevention of Acute Pancreatitis Complicating Liver Failure

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Mechanisms and Prevention of Acute Pancreatitis Complicating Liver Failure

Liver failure is a severe destruction of hepatocytes triggered by various pathological factors, leading to significant liver dysfunction. In clinical practice, it is often characterized by ascites, jaundice, hepatorenal syndrome, and infections, commonly associated with systemic inflammatory response syndrome. Its onset is rapid, the progression is swift, and it has many complications, making it extremely … Read more

Research Progress on Combined Artificial Liver

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Research Progress on Combined Artificial Liver

The liver is one of the most metabolically active organs in the body and is crucial for maintaining the internal environment balance. Its main functions include the secretion of endogenous active substances and the transformation or clearance of toxic substances. When liver function is impaired due to factors such as viruses, drugs, or surgery, an … Read more

Artificial Liver Treatment in Early Stage Liver Failure

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Artificial Liver Treatment in Early Stage Liver Failure

Early-stage liver failure refers to a state of disease where the patient’s liver function deteriorates sharply, posing a risk of liver failure but not yet meeting the diagnostic criteria for liver failure. Early warning of the risk of liver failure and timely intervention can help improve patient prognosis and reduce the economic burden on patients. … Read more

Current Status of ACLF Animal Model Research

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Current Status of ACLF Animal Model Research

Acute-on-chronic liver failure (ACLF) refers to a clinical syndrome characterized by acute decompensation of liver function in a short period on the basis of chronic liver disease. The pathogenesis of ACLF is complex, the condition is perilous, progresses rapidly, and is accompanied by multiple organ failure, with a high short-term mortality rate and no specific … Read more

Clinical Practice and Research Progress of Artificial Liver Treatment

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Clinical Practice and Research Progress of Artificial Liver Treatment

Hepatic failure is a common critical condition caused by severe liver dysfunction, particularly acute (subacute) liver failure and subacute liver failure, which progress rapidly and have a high mortality rate. The basic principle of the artificial liver support system is to temporarily replace part of the liver’s function through extracorporeal mechanical, physicochemical, and biological devices, … Read more