HER2-positive breast cancer

Recent Advances in ADC Therapy for Active Brain Metastases in Breast Cancer

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Recent Advances in ADC Therapy for Active Brain Metastases in Breast Cancer

Brain metastases are a common and severe complication of metastatic breast cancer (MBC), with approximately 20% to 30% of patients experiencing brain metastases[1]. Among these, the incidence of brain metastases in HER2-positive MBC patients can reach 30% to 55%[2]; the incidence is also high in HER2-negative patients[3]. This makes MBC the second leading cause of … Read more

Progression-Free Survival Increased Fivefold, Intracranial Response Rate at 65.7%! ‘Miraculous Anti-Cancer Drug’ Solves the Treatment Challenge of Breast Cancer Brain Metastases

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Progression-Free Survival Increased Fivefold, Intracranial Response Rate at 65.7%! 'Miraculous Anti-Cancer Drug' Solves the Treatment Challenge of Breast Cancer Brain Metastases

What else can DS-8201 not do? Recently, the “miraculous anti-cancer drug” DS-8201 announced data from its DESTINY-Breast03 trial involving patients with brain metastases[1]: Among 43 patients with HER2-positive breast cancer brain metastases treated with DS-8201, the median progression-free survival reached 15.0 months, with intracranial objective response rate and overall objective response rate at 65.7% and … Read more