anticoagulation

Anticoagulant Drug Selection After Left Atrial Appendage Closure

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Anticoagulant Drug Selection After Left Atrial Appendage Closure

Currently, for patients with non-valvular atrial fibrillation (NVAF) who cannot tolerate or do not wish to undergo long-term anticoagulation therapy to prevent stroke, percutaneous left atrial appendage closure (LAAC) is an effective and safe surgical method for stroke prevention in atrial fibrillation (AF) patients. Regarding the management after LAAC, guidelines recommend short-term anticoagulation post-surgery, followed … Read more

Discussion on Anticoagulation Optimization After Left Atrial Appendage Occlusion

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Discussion on Anticoagulation Optimization After Left Atrial Appendage Occlusion

Left atrial appendage (LAA) occlusion has emerged as a non-valvular atrial fibrillation (AF) stroke prevention strategy in recent years. Similar to other congenital heart defect occlusion procedures, patients undergoing LAA occlusion require anticoagulation therapy to prevent device-related thrombus (DRT) events. However, the anticoagulation strategies post-LAA occlusion in China are not yet fully standardized, and clinicians … Read more

Understanding Protein C, Anti-Protein C Antibodies, CRP, Immunoglobulins, and Albumin

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Click the title below to follow this accountContinuously obtain knowledge and information on adverse pregnancy 　●Comprehensively understand the knowledge points related to pregnancy failure, avoid detours, and quickly have a baby! 　●Flexibly use the search function of the public account, access the menu bar, and use keyword auto-replies to quickly read previously published articles or … Read more

Latest Research Progress on Anticoagulation Therapy After Left Atrial Appendage Closure

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Latest Research Progress on Anticoagulation Therapy After Left Atrial Appendage Closure

With the continuous advancement of medical technology, left atrial appendage closure (LAAC) has become increasingly widespread in clinical applications, bringing hope to many patients with atrial fibrillation. Antithrombotic therapy runs through the entire process of LAAC and is one of the core issues of LAAC. However, there is currently no consensus on how to formulate … Read more

Exploring Half-Dose DOAC Therapy to Prevent DRT and Reduce Bleeding Risk

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Exploring Half-Dose DOAC Therapy to Prevent DRT and Reduce Bleeding Risk

On October 13, 2021, a prospective, non-randomized study published in JACC Intervention indicated that after successful left atrial appendage closure (LAAC) using the WATCHMAN device (Boston Scientific), an anticoagulation strategy centered on half-dose direct oral anticoagulants (DOAC) might improve overall surgical outcomes and reduce the occurrence of device-related thrombosis (DRT) compared to standard anticoagulation therapy … Read more

Left Atrial Appendage Closure: DRT Detection and Management

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Left Atrial Appendage Closure: DRT Detection and Management

In the fields of cardiac pacing, electrophysiology, coronary intervention, traditional structural heart disease, or new structural heart disease interventions, there is a risk of device-related thrombosis (DRT), and the left atrial appendage closure (LAAC) is no exception. As one of the postoperative complications, DRT remains a key focus during postoperative follow-ups. Recently, Professor Zeng Jie … Read more

Exploring Left Atrial Appendage Occlusion Device-Related Thrombosis: Clinical Impact, Risk Prediction, Differentiation, and Management

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Exploring Left Atrial Appendage Occlusion Device-Related Thrombosis: Clinical Impact, Risk Prediction, Differentiation, and Management

Left Atrial Appendage Occlusion (LAAO) surgery is an effective alternative treatment to long-term oral anticoagulants (OAC), aimed at preventing thromboembolic events associated with non-valvular atrial fibrillation. The occurrence of device-related thrombosis (DRT) after LAAO has been a long-standing concern for both clinicians and patients, making it an important observation during postoperative follow-up. Recently, the Journal … Read more

ICC 2019 | Yao Hua and Pan Lei: Interpretation of Acute Pulmonary Embolism Guidelines

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ICC 2019 | Yao Hua and Pan Lei: Interpretation of Acute Pulmonary Embolism Guidelines

Pulmonary embolism is a common cardiovascular disease, which can be further subdivided into deep vein thrombosis and pulmonary embolism. In recent years, the incidence of pulmonary embolism in China has been increasing year by year, and how to timely and accurately identify patients with pulmonary embolism and provide appropriate treatment has gradually become a focus … Read more

Professor Zhang Ling: Advances and Breakthroughs in Severe Blood Purification Technology

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On January 15, 2025, DXY invited Sichuan University West China Hospital to co-host the “2024 Year-End Review in Nephrology” conference. During the meeting, Professor Zhang Ling from the Department of Nephrology at West China Hospital shared insights on the topic of “Advances and Breakthroughs in Severe Blood Purification Technology”, combining the latest research progress with … Read more