Stereodivergent Synthesis of Allylic All-Carbon Quaternary Centers by Bimetallic Iridium/Magnesium-Catalyzed Allylic Alkylation
The research team led by Liu Yangbin from Peking University and Feng Xiaoming from Sichuan University optimized conditions using benzothiazole acetamide and trisubstituted allylic carbonates, successfully applying the “iridium/magnesium cooperative catalysis strategy” to the asymmetric allylic alkylation reaction of trisubstituted allylic electrophiles with non-cyclic nucleophiles (α-benzothiazole acetamide). Abstract The stereodivergent synthesis of structural motifs bearing … Read more