Literature Sharing | J Am Chem Soc: Quantitative Analysis of Single-Cell High-Throughput Multi-Omics Aptomics

Literature Sharing | J Am Chem Soc: Quantitative Analysis of Single-Cell High-Throughput Multi-Omics Aptomics

High-throughput sequencing technology is driving the life sciences towards a quantitative paradigm, but the sequencing technologies for antibodies, glycans, and other non-directly measurable molecules face challenges such as complex coupling steps, steric hindrance, and the labor-intensive nature of enzymatic chemical labeling. Aptamers, as nucleic acid molecules that can be sequenced directly, possess high specificity, broad … Read more

New Pathway for ADCs – Dual Payload ADCs

New Pathway for ADCs - Dual Payload ADCs

Currently, all marketed ADC drug molecules use a single small molecule toxin as the effective payload, but challenges such as drug resistance and limited therapeutic effects still exist. Therefore, clinical chemotherapy regimens often employ combinations of multiple drugs for combination therapy. Considering the clinical efficacy of combination chemotherapy, ADC drugs with two or more effective … Read more

Case Report: HER2 Negative to Positive Conversion in Breast Cancer Re-biopsy?! Benefits of DS-8201 Treatment

Case Report: HER2 Negative to Positive Conversion in Breast Cancer Re-biopsy?! Benefits of DS-8201 Treatment

Open the public account and set it as a “star”. Follow us to learn more about cancer information!~ Breast Cancer In recent years, the treatment of breast cancer has been influenced by the practice of precision oncology, requiring personalized medical care based on specific tumor characteristics. The treatment of breast cancer primarily depends on the … Read more