multiplex detection

AI-Mediated Encoding-Decoding for Multiplexed Microfluidic Digital Immunoassay Based on Computer Vision

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AI-Mediated Encoding-Decoding for Multiplexed Microfluidic Digital Immunoassay Based on Computer Vision

Hello everyone, today I would like to share a paper published in 2023 in Talanta, titled “Computer Vision-Based Artificial Intelligence-Mediated Encoding-Decoding for Multiplexed Microfluidic Digital Immunoassay.” This paper develops a multidimensional digital immunoassay through particle-based encoding and AI-based decoding, achieving high sensitivity and convenient multiplex detection. The encoded information in the characteristics of microspheres, including … Read more

Wide Dynamic Range Multiplex Digital CRISPR Chip for Absolute Quantification of Nucleic Acids

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Wide Dynamic Range Multiplex Digital CRISPR Chip for Absolute Quantification of Nucleic Acids

01Research Overview With the rapid development of molecular diagnostic technologies, digital CRISPR technology has become an important tool for nucleic acid detection due to its single-molecule counting and absolute quantification capabilities. However, traditional digital CRISPR platforms face significant challenges in several aspects. Firstly, most existing platforms adopt equal-volume microcavity designs, which typically cover a dynamic … Read more