In October 2020, the research groups of Frank C. Schroeder at Cornell University and Joshua A. Baccile at the University of Tennessee published a collaborative research paper titled “Deep Interrogation of Metabolism Using a Pathway-Targeted Click-Chemistry Approach” in J. Am. Chem. Soc., developing a click chemistry enrichment strategy named DIMEN (Deep Interrogation of Metabolism via … Read more
Friends, please click on the above「Medical Intelligence Hardcore Talk」/ Click on the above「 . . .」/ Select「Set as Star」 By 2025, the global ADC (Antibody-Drug Conjugate) market size will exceed $30 billion, yet the confusion among oncologists remains—half of the patients develop resistance during treatment, 15% experience severe side effects due to off-target effects, not … Read more
–01– Introduction The announcement of the 2022 Nobel Prize in Chemistry brought the cutting-edge technology of “Click Chemistry” into the public eye. The groundbreaking work of three scientists has not only revolutionized the field of organic synthesis but also opened new pathways for cancer treatment—specifically, the development of Antibody-Drug Conjugates (ADC) is advancing towards a … Read more