Deep Interrogation of Metabolism Using a Pathway-Targeted Click-Chemistry Approach

Deep Interrogation of Metabolism Using a Pathway-Targeted Click-Chemistry Approach

In October 2020, the research groups of Frank C. Schroeder at Cornell University and Joshua A. Baccile at the University of Tennessee published a collaborative research paper titled “Deep Interrogation of Metabolism Using a Pathway-Targeted Click-Chemistry Approach” in J. Am. Chem. Soc., developing a click chemistry enrichment strategy named DIMEN (Deep Interrogation of Metabolism via … Read more

Uncovering the Molecular Landscape of Tetracycline Family Natural Products through Bacterial Genome Mining

Uncovering the Molecular Landscape of Tetracycline Family Natural Products through Bacterial Genome Mining

Click the “Nanjing IFB” above to follow us! Hello everyone, today I would like to share an article published inJACS titled:Uncovering the Molecular Landscape of Tetracycline Family Natural Products through Bacterial Genome Mining. The corresponding author is Researcher Guohui Pan from the Institute of Microbiology, Chinese Academy of Sciences.Researcher Guohui Pan’s research focuses on the … Read more

Revision of the Formycin A and Pyrazofurin Biosynthetic Pathways Reveals Specificity for D‑Glutamic Acid and a Cryptic N‑Acylation Step During Pyrazole Core Formation

Revision of the Formycin A and Pyrazofurin Biosynthetic Pathways Reveals Specificity for D‑Glutamic Acid and a Cryptic N‑Acylation Step During Pyrazole Core Formation

Click the “Nanjing University IFB” above to follow us! Hello everyone, today I would like to share a recent article published in the Journal of the American Chemical Society:Revision of the Formycin A and Pyrazofurin Biosynthetic Pathways Reveals Specificity for D‑Glutamic Acid and a Cryptic N‑Acylation Step During Pyrazole Core Formation, with the corresponding author … Read more

Biosynthesis of Dothideomins Reveals a Fungal P450 That Constructs the Tricyclo[5.2.2.0.4,8]undecane-Imbedded Core Skeleton

Biosynthesis of Dothideomins Reveals a Fungal P450 That Constructs the Tricyclo[5.2.2.0.4,8]undecane-Imbedded Core Skeleton

Click the “Nanjing IFB” above to follow us! Hello everyone, today I would like to share a recent article published in theJACS journal titled “Biosynthesis of Dothideomins Reveals a Fungal P450 That Constructs the Tricyclo[5.2.2.0.4,8]undecane-Imbedded Core Skeleton”, with Professor Li Dehai from the School of Medicine, Ocean University of China as the corresponding author, who … Read more