Synergistic Construction of Chiral Carbon Centers via Photocatalytic Nickel Catalysis

Synergistic Construction of Chiral Carbon Centers via Photocatalytic Nickel Catalysis

Image source: J. Am. Chem. Soc.Introduction: The enantioselective alkyl-alkyl cross-coupling is a powerful and challenging strategy for constructing three-dimensional molecular structures, which hold significant value in organic chemistry and medicinal chemistry. Although radical-radical cross-coupling provides a feasible pathway to achieve this goal, controlling the cross-selectivity and enantioselectivity between two different alkyl radicals remains a significant … Read more