ATF3/SPI1/SLC31A1 Pathway Promotes Copper Death Induced by AGEs in Diabetic Myocardial Injury

ATF3/SPI1/SLC31A1 Pathway Promotes Copper Death Induced by AGEs in Diabetic Myocardial Injury

Shengqi Huo 1, Qian Wang 1, Wei Shi 1, Lulu Peng 1, Yue Jiang 1, Mengying Zhu 1, Junyi Guo 1, Dewei Peng 1, Moran Wang 1, Lintong Men 1, Bingyu Huang 1, Jiagao Lv 1, Li Lin 12023 Jan 14;24(2):1667. doi: 10.3390/ijms24021667. Affiliationsexpand PMID: 36675183 PMCID: PMC9862315 DOI: 10.3390/ijms24021667 Research Background The acquisition, distribution, … Read more

Desmoplakin Cardiomyopathy Mimicking Viral Myocarditis

Desmoplakin Cardiomyopathy Mimicking Viral Myocarditis

*For Medical Professionals Only The clinical characteristics and imaging manifestations of myocarditis can overlap with other inflammatory or arrhythmic cardiomyopathies. Desmoplakin (DSP) is an important cardiac structural protein. Mutations in the DSP gene are associated with a variant of arrhythmogenic right ventricular cardiomyopathy (ARVC). Interestingly, this unique genetic cardiomyopathy may also present with myocarditis and … Read more

Expert Consensus on the Integrated Diagnosis and Treatment of Sepsis-Induced Cardiomyopathy (2022)

Expert Consensus on the Integrated Diagnosis and Treatment of Sepsis-Induced Cardiomyopathy (2022)

Sepsis is one of the common severe complications in critically ill patients with trauma, burns, shock, and infections. It remains a significant threat to human health, characterized by high incidence, high mortality, and high treatment costs. Millions of people are diagnosed with sepsis globally each year, with a mortality rate ranging from 16.7% to 33.3%. … Read more