Differences in Classification of TP53-MDS, MDS/AML, and AML by WHO and ICC

Differences in Classification of TP53-MDS, MDS/AML, and AML by WHO and ICC

Image Source: Xiao W, Nardi V, Stein E, Hasserjian RP. A practical approach on the classifications of myeloid neoplasms and acute leukemia: WHO and ICC. J Hematol Oncol. 2024;17(1):56. Published 2024 Jul 29. For TP53 positive MDS, MDS/AML, and AML, the requirements for TP53 mutations differ, leading to the discrepancies in classifications of TP53 positive … Read more

Chordoma Classification Notes: Understanding the 5th Edition by WHO

Chordoma Classification Notes: Understanding the 5th Edition by WHO

Chordoma Definition Primary, malignant bone neoplasm showing notochordal differentiation; it comprises conventional, poorly differentiated and dedifferentiated types. ICD-O Codes 9372/3 Conventional chordoma 9370/3 Poorly differentiated chordoma 9372/3 Dedifferentiated chordoma ICD-11 Codes 2B5K & XH9GH0 unspecified malignant soft tissue tumours or sarcomas of bone or articular cartilage of other or unspecified sites & Chordoma NOS 2B5K … Read more