J. Am. Chem. Soc.: Analysis of Mitochondria-Specific Methionine Sulfoxide Reductase Activity Based on Dual-Channel Phosphorescence Ratiometry and Lifetime Imaging
The redox homeostasis of mitochondria is crucial for mitochondrial function and cellular status, achieved through the intricate interplay between oxidative stress factors (such as reactive oxygen species/reactive nitrogen species ROS/RNS) and the antioxidant defense system. An imbalance in redox state can lead to protein damage, ultimately resulting in tissue injury. For instance, methionine residues in … Read more