Photocatalytic Indole Ring ‘Editing’ to Quinazoline for Tryptophan Site-Specific Peptide Modification
Image source: J. Am. Chem. Soc.Introduction:Site-specific late-stage modification of natural peptide chains is an ideal strategy for developing bioactive peptide analogs in an efficient and economical manner. The emerging concept of scaffold editing provides new ideas for developing next-generation methods for late-stage peptide modifications. This study developed a simple tryptophan-specific late-stage modification method for peptide … Read more
