From ADC to DAC: Tackling the ‘Undruggable’ Lifeline? (Data Updated to AACR 2025)
In previous discussions about dual payloads, it was mentioned that payload diversity is a crucial consideration in the future development of ADCs (ADC: Payload Evolution and Dual Payload Strategy). There are two main reasons for this: first, the existing toxin payloads have relatively singular modes of action, and treatment strategies after drug resistance need to … Read more