glutamate

An Engineered Supramolecular Fluorescent Chemosensor for Multiscale Visualization of Glutamate Dynamics in Living Systems

by
An Engineered Supramolecular Fluorescent Chemosensor for Multiscale Visualization of Glutamate Dynamics in Living Systems

Hello everyone, today I would like to introduce a paper on an engineered supramolecular fluorescent chemosensor for multiscale visualization of glutamate dynamics in living systems. Glutamate (Glu) is the main excitatory neurotransmitter in the central nervous system and plays a crucial role in maintaining normal neural activity. Once the level of Glu in the central … Read more

Engineering Supramolecular Fluorescent Chemical Sensors for Dynamic Multiscale Visualization of Glutamate in Living Systems

by
Engineering Supramolecular Fluorescent Chemical Sensors for Dynamic Multiscale Visualization of Glutamate in Living Systems

[East China Normal University Tian Yang]Published on 2025.9.3 Research Highlights Glutamate (Glu) plays a critical role in the brain, and the ability to directly measure glutamate activity is essential for understanding its physiological functions and pathological processes. This paper presents a series of glutamate sensors (TympGn) designed based on the indicator displacement assay (IDA). The … Read more

Exercise May Reduce the Toxic Effects of Excess Glutamate in the Brain

by
Exercise May Reduce the Toxic Effects of Excess Glutamate in the Brain

Recently, a study published in the international journal Applied Physiology, Nutrition, and Metabolism by researchers from the University of Guelph found that exercise may potentially reduce the toxic accumulation of glutamate in the brain, while also decreasing the severity of various brain disorders, such as Huntington’s disease. Glutamate is an amino acid that forms proteins, … Read more

Research Advances in Glutamate and γ-Aminobutyric Acid Homeostasis Imbalance in Major Depressive Disorder

by
Research Advances in Glutamate and γ-Aminobutyric Acid Homeostasis Imbalance in Major Depressive Disorder

【Citation Format】Li Mian, Tan Zhonglin, Wu Yue, et al. Research advances in glutamate and γ-aminobutyric acid homeostasis imbalance in major depressive disorder[J]. Chinese Journal of Nervous and Mental Diseases, 2023, 49(12): 758-764. 【Cite this article】LI Mian, TAN Zhonglin, WU Yue, et al. Research advances in glutamate and γ-aminobutyric acid homeostasis imbalance in major depressive disorder[J]. … Read more