decarboxylative allylation

Unlocking Chromium Decarboxylative Ligand-to-Metal Charge Transfer: Efficient and Redox-Neutral Allylation of Aldehydes Using Carboxylic Acids

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Unlocking Chromium Decarboxylative Ligand-to-Metal Charge Transfer: Efficient and Redox-Neutral Allylation of Aldehydes Using Carboxylic Acids

Recently, Professor Alexander W. Schuppe’s team from Vanderbilt University reported in J. Am. Chem. Soc. the decarboxylative ligand-to-metal charge transfer (LMCT) reaction of photoinduced Cr (III) carboxylate complexes, applying it to the stereoselective Nozaki-Hiyama-Kishi (NHK) allylation reaction. This method directly utilizes carboxylic acids without the need for external redox reagents, achieving good yields and high … Read more

Photoinduced Decarboxylative Allylation: Dual Atom Substitution for sp3 Fragment Skeleton Editing

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Photoinduced Decarboxylative Allylation: Dual Atom Substitution for sp3 Fragment Skeleton Editing

Image source: J. Am. Chem. Soc.Introduction:Professor Ruben Martin reported a photoinduced palladium-catalyzed interceptive decarboxylative allylation reaction. This strategy innovatively achieves atom pair exchange and a series of skeletal contraction and extension reactions, providing a non-traditional retrosynthetic approach for complex molecule construction, while offering a modular and versatile synthetic tool for rapidly and efficiently obtaining sp3 … Read more