Why Cystatin C Is Highly Regarded? Tips You Should Know

Why Cystatin C Is Highly Regarded? Tips You Should Know

Author: Gao JieUnit: Shanxi Bethune Hospital Laboratory Serum cystatin C (CysC), also known as cysteine protease inhibitor C, is a low molecular weight, non-glycosylated basic protein with a molecular weight of approximately 13kD. Almost all nucleated cells in the body’s tissues can continuously produce CysC at a constant rate. CysC can freely pass through the … Read more

Macrophage Zc3h12c Limits Tissue Inflammation and Injury via Alternative Splicing of Pre-mRNA

Macrophage Zc3h12c Limits Tissue Inflammation and Injury via Alternative Splicing of Pre-mRNA

Article Highlights RNA-binding proteins regulate post-transcriptional gene translation, but the macrophage-specific role of Zc3h12c remains unclear. Here, we characterized the role of Zc3h12c in macrophages using Tnfrsf11aCre-Zc3h12cflox/flox mice. Both Tnfrsf11a and Zc3h12c are highly expressed in renal tissues of patients with chronic kidney disease and are positively correlated with interstitial fibrosis scores. Single-cell RNA sequencing … Read more

3D Printing a Kidney? Where Are We in the Development of Artificial Kidneys?

3D Printing a Kidney? Where Are We in the Development of Artificial Kidneys?

3D printing technology has entered the medical field, particularly in orthopedics. For example, through 3D printing technology, it is possible to create highly precise and personalized bone prosthetics that are best suited for patients, which can better assist doctors in handling some difficult cases. Therefore, many kidney patients are very concerned about this issue! Since … Read more

Impact of Renal Function on Myocardial Remodeling and Outcomes in Patients with Moderate Aortic Stenosis

Impact of Renal Function on Myocardial Remodeling and Outcomes in Patients with Moderate Aortic Stenosis

DOI: http://doi.org/10.1016/j.echo.2025.04.008 The Journal of the American Society of Echocardiography recently published an online research paper titled Impact of Renal Function on Myocardial Remodeling and Outcomes in Patients with Moderate Aortic Stenosis on April 17, 2025. This study focuses on the impact of renal function on myocardial remodeling and clinical outcomes in patients with moderate … Read more