Bone Marrow Failure

Classification of ICC Pediatric Refractory Cytopenia and MDS

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Classification of ICC Pediatric Refractory Cytopenia and MDS

Original Authors: Rudelius M, Weinberg OK, Niemeyer CM, Shimamura A, Calvo KR. Background/Introduction ICC classifies pediatric myelodysplastic syndromes (MDS) separately from adult MDS. This separation acknowledges the unique biological characteristics of pediatric and adolescent MDS, which differ significantly from those of elderly MDS in terms of genetic landscape and treatment approaches. Pediatric MDS lacks recurrent … Read more

Evaluation of Morphology in Myeloid Neoplasms: ICC Series Part Three

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Evaluation of Morphology in Myeloid Neoplasms: ICC Series Part Three

MorphologyMorphologyPeripheral blood specimenPeripheral blood specimen A well-prepared and well-stained peripheral blood smear should be examined and correlated with the patient’s blood counts. Cytology of leukocytes, red blood cells, and platelets should be evaluated. A manual 200-cell leukocyte differential count (or counting of all available cells in markedly leukopenic cases) should be performed as part of … Read more