3D fluorescence

A Novel Multiparameter Sensor for Shake Flask Cultivations: Online Monitoring of Biomass, Dissolved Oxygen, and Fluorescence for Comprehensive Bioprocess Characterization

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A Novel Multiparameter Sensor for Shake Flask Cultivations: Online Monitoring of Biomass, Dissolved Oxygen, and Fluorescence for Comprehensive Bioprocess Characterization

Shake flasks are one of the most widely used cultivation vessels in biotechnological process development. In recent years, several new technologies have been reported for online monitoring of various parameters such as oxygen, pH values, or biomass. However, most reports only involve monitoring a single parameter per shake flask. This study evaluates the capability of … Read more

3D Fluorescent Sensor Driven by Deep Learning: Rapid Recognition of Serum Carbohydrates Using CuO Nanomaterials

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3D Fluorescent Sensor Driven by Deep Learning: Rapid Recognition of Serum Carbohydrates Using CuO Nanomaterials

Introduction Based on the oxidase-like properties of copper oxide nanoparticles (CuO NPs), this study developed a sensor array method that combines three-dimensional fluorescence (3D FL) spectroscopy with deep convolutional neural networks (CNN) for the high-precision and high-sensitivity identification and quantification of carbohydrates in serum and complex environments. The model achieved an accuracy of 99–100% in … Read more