A Novel Multiparameter Sensor for Shake Flask Cultivations: Online Monitoring of Biomass, Dissolved Oxygen, and Fluorescence for Comprehensive Bioprocess Characterization

A Novel Multiparameter Sensor for Shake Flask Cultivations: Online Monitoring of Biomass, Dissolved Oxygen, and Fluorescence for Comprehensive Bioprocess Characterization

Shake flasks are one of the most widely used cultivation vessels in biotechnological process development. In recent years, several new technologies have been reported for online monitoring of various parameters such as oxygen, pH values, or biomass. However, most reports only involve monitoring a single parameter per shake flask. This study evaluates the capability of … Read more