Cu-Catalyzed Ullmann Coupling with Anionic o-Phenylenediamine Ligands
from J. Am. Chem. Soc. Hello, everyone! Those who often work in medicinal chemistry know that Cu-catalyzed Ullmann coupling, while a substitute for Buchwald coupling, has not been as effective due to the difficulty of Cu oxidation addition. Upon reflection, electron-rich ligands are beneficial for oxidation addition, and previous neutral ligands were clearly insufficient. So … Read more