Drug-Antibody Ratio

Introduction to Antibody-Drug Conjugates (ADC)

by
Introduction to Antibody-Drug Conjugates (ADC)

Since the first use of cytotoxic chemicals to treat cancer, oncologists have been searching for ways to improve efficacy without significantly increasing overall toxicity to patients. One of the methods attempted to enhance the killing effect on tumor cells is the use of cytotoxic agents with potency at picomolar or lower levels (such as microtubule … Read more

Physicochemical Analysis and Structural Characterization of Antibody-Drug Conjugates (ADCs)

by
Physicochemical Analysis and Structural Characterization of Antibody-Drug Conjugates (ADCs)

Preface Preface Author Cloud Assistant Antibody-drug conjugates (ADCs) are a class of emerging drugs that combine the advantages of both antibodies and small molecule toxins. Compared to traditional cytotoxic drugs, ADCs have the advantages of strong targeting and fewer side effects, making them promising in the field of tumor therapy. To date, 11 ADC drugs … Read more