Complement and Disease: Misdiagnosis Strategies for Atypical Hemolytic Uremic Syndrome
Atypical hemolytic uremic syndrome (aHUS) is a type of complement-mediated thrombotic microangiopathy (TMA), characterized by microangiopathic hemolytic anemia (MAHA), thrombocytopenia, and multi-organ damage as typical manifestations, with infection and pregnancy being the main triggers.[1] The condition of aHUS is usually quite critical. In the pre-complement treatment era, the mortality rate during the acute phase was … Read more