Skeletal Editing Strategy from Pyridine to Pyridazine by Sungwoo Hong at KAIST
The Korea Advanced Institute of Science and TechnologySungwoo Hong and his team reported a direct skeletal editing strategy that succinctly converts pyridine to pyridazine by replacing carbon atoms with nitrogen atoms. This practical method demonstrates broad functional group tolerance, allowing the transformation of various complex molecules and commercially available drugs into their biologically equivalent pyridazine … Read more