Pathophysiological Mechanisms of Lymph Node Metastasis Differences Between HCC and ICC: Anatomical, Molecular Biology, and Microenvironment Factors
1. Introduction: Differences in Metastasis of Malignant Liver Tumors Primary liver cancer is the third leading cause of cancer-related deaths worldwide, with hepatocellular carcinoma (Hepatocellular Carcinoma, HCC) and intrahepatic cholangiocarcinoma (Intrahepatic Cholangiocarcinoma, ICC) being the two main histological types, accounting for approximately 75%-85% and 10%-15% of primary liver cancer cases, respectively 1. Although both malignancies … Read more