JAK-STAT signaling

Mechanistic Study of tsRNA-GlyGCC Regulating the SPIB/JAK-STAT Pathway to Promote Chemoresistance in Colorectal Cancer

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Mechanistic Study of tsRNA-GlyGCC Regulating the SPIB/JAK-STAT Pathway to Promote Chemoresistance in Colorectal Cancer

The Photothermal Biology Database (https://grswsci.top) is a comprehensive, user-friendly, one-click interactive web resource, initiated in 2023, officially launched on April 1, 2024, with cumulative visits exceeding 110,000. It is used to analyze various cancer omics data, including genomics, transcriptomics, proteomics, epigenetics, single-cell sequencing, spatial transcriptomics, etc., providing easily accessible publicly available cancer omics data, allowing … Read more

Gene-Encoded Biosensor STATeLights: A Breakthrough Tool for Real-Time Visualization of STAT Activation in Live Cells

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Gene-Encoded Biosensor STATeLights: A Breakthrough Tool for Real-Time Visualization of STAT Activation in Live Cells

In the field of cell signaling research, the signal transducer and activator of transcription (STAT) family plays a critical role, with abnormal activation closely related to various diseases such as cancer and autoimmune diseases, making it an important drug target. However, the long-standing lack of effective tools for real-time monitoring of STAT activation has hindered … Read more