genomic analysis

HiFi-C Sample Submission Process: How to Prepare for Optimal Data Collection

by
HiFi-C Sample Submission Process: How to Prepare for Optimal Data Collection

HiFi-C (High-Fidelity Chromosome Conformation Capture) is a high-fidelity chromatin conformation capture technology based on high-throughput sequencing. It captures the spatial interactions of chromatin within the nucleus, allowing for precise analysis of the three-dimensional structure of the genome (such as TADs and chromatin loops) and the interaction patterns of gene regulatory elements (promoter-enhancer interactions). This technology … Read more

Population History Inference Using SMC++

by
Population History Inference Using SMC++

1Terminology Explanation Effective Population (Ne): An ideal population that, under the influence of random genetic drift, can produce the same allele frequency distribution or an equal number of inbred individuals is referred to as the effective population size of that population, which is a theoretical assessment of genetic diversity and evolutionary potential.The larger the Ne … Read more