Understanding Antibody-Drug Conjugates (ADCs)
From “Magic Bullets” to the Birth of ADC Drugs As early as 1913, Paul Ehrlich first proposed the concept of “magic bullets” and drug targeting. However, it wasn’t until the rapid development of antibody technology in the 1970s that the first antibody-drug conjugate (ADC) — Gemtuzumab ozogamicin (GO), targeting CD33, was approved by the FDA … Read more