What is the Difference Between Procalcitonin and C-Reactive Protein?

What is the Difference Between Procalcitonin and C-Reactive Protein?

C-Reactive Protein (CRP) is an acute phase inflammatory protein that was first discovered and named by Tillet and Francis in 1930 while studying the serum of patients infected with Streptococcus pneumoniae.[1]CRP is primarily synthesized in hepatocytes, initially produced as a monomer and then assembled into a pentamer in the endoplasmic reticulum of the source cell. … Read more

C-Reactive Protein vs Procalcitonin: Which Has the Advantage?

C-Reactive Protein vs Procalcitonin: Which Has the Advantage?

Authors: Wang Yixin, Sun Yunhui Affiliation: The First Affiliated Hospital of Jiamusi University 1. Procalcitonin Procalcitonin (PCT) is a non-hormonal precursor peptide glycoprotein that is released into the patient’s circulatory system as a soluble protein under conditions of severe systemic infection, particularly bacterial infections. Under normal physiological conditions, PCT, transcribed from the CALC-1 gene, is … Read more