E/Z stereodivergent synthesis

Purdue University,Professor Christopher Uyeda’s team utilized the principles of asymmetric catalysis to achieve control over the E/Z stereoisomers in the formation of non-chiral alkene products. This reaction involves cobalt-catalyzed reductive coupling of 1,1-dichloroalkenes with allylic alcohols, resulting in the formation of skipped 1,4-diene products. Abstract Catalytic asymmetric reactions are primarily used to install new stereogenic … Read more