Benzidine Rearrangement: A Name Reaction Explained
In 1863, Hofmann reported the rearrangement of diphenylhydrazine to 4,4-diaminobiphenyl (aniline) under acid catalysis, known as the benzidine rearrangement. When diphenylhydrazine contains a para-substituent, the product obtained is para-aminobiphenyl, and this reaction is referred to as the Semidine rearrangement. Reaction Mechanism Reaction Examples References 1. Hofmann, A. W., Proc. Roy. Soc. London, 1863, 12, 576. … Read more