Click the blue text to follow meOn the battlefield against cancer, a new type of “weapon” is rising – the ADC (Antibody-Drug Conjugate) anti-cancer drug independently developed in China. The emergence of this drug has not only attracted the attention of the global pharmaceutical industry but has also given countless patients new hope. Why are American pharmaceutical companies willing to invest 7 billion dollars for collaboration? Let’s explore.1. Targeted Conjugation Technology: Precisely Striking Cancer Cells, Minimizing Collateral DamageTraditional ADC drugs, during treatment, act like a shotgun, with toxins randomly binding to antibodies, resulting in an error rate as high as 50%. This means that while attacking cancer cells, normal cells may also be harmed, bringing unnecessary side effects to patients.However, the targeted conjugation technology developed by Chinese pharmaceutical companies has completely changed this situation. By precisely binding toxins to the “golden sites” on antibodies, the error rate has been reduced to just 5%. This is akin to upgrading from a shotgun to a GPS-guided missile, capable of accurately striking targets and minimizing collateral damage. This technological breakthrough has marked an important step forward for Chinese ADC drugs in precision treatment, providing patients with safer and more effective treatment options.
2. Head-to-Head Experimental Data Crushes: Doubling Survival Time, Lower Side EffectsIn clinical trials, the performance of Chinese ADC drugs has been remarkable. In head-to-head comparisons with international competitors, a domestic ADC drug has extended progression-free survival by two years, with an objective response rate as high as 78%, while side effects are 30% lower than those of competitors. This is like playing a game where others spend money to buy equipment, while we simply cheat. This advantage is not only reflected in treatment efficacy but also in the quality of life and survival quality of patients. Patients can maintain a better physical condition for a longer time and enjoy life, which is undoubtedly a great comfort and support for them and their families.3. High International Pricing, Domestic Benefits: Global Patients Benefit, Domestic Patients RejoiceChinese ADC drugs are priced high in the international market, leveraging technological advantages and innovation to achieve a premium, capturing the global market. However, domestically, these drugs follow the medical insurance route, making them affordable for more patients. This dual-track strategy not only allows Chinese pharmaceutical companies to secure a place in the global market but also greatly benefits domestic patients. In the global pharmaceutical market, this strategy of Chinese pharmaceutical companies demonstrates their care for domestic patients and confidence in the global market, enabling more patients to enjoy advanced treatment technologies, improving survival rates and quality of life.4. The Rise of Chinese Innovative Drugs: From “Imitation” to “Leading”, A New Hope for Global PatientsIn the past, ADC technology was monopolized by Europe and the United States, and Chinese pharmaceutical companies were once eager for technology. Now, the plot has reversed; Chinese pharmaceutical companies have achieved a leap from following to leading through technological innovation and business acumen. There are dozens of Chinese ADC drugs waiting for approval from the US FDA, and global patients are waiting for life-saving drugs made in China. The rise of Chinese innovative drugs has not only changed the landscape of the global pharmaceutical market but has also elevated China’s status in the international pharmaceutical field. This marks a significant breakthrough in the technological innovation and research and development capabilities of the Chinese pharmaceutical industry, enabling it to provide higher quality and more effective treatment options for global patients.The rise of Chinese innovative drugs is the result of the hard work and relentless efforts of countless researchers. They have earned the respect of the world for the Chinese pharmaceutical industry with their wisdom and sweat. Next time someone says that China only knows how to make generic drugs, throw this article in their face. Our biological missiles are specifically designed to tackle various challenges. The rise of Chinese ADC anti-cancer drugs not only brings good news to domestic patients but also makes significant contributions to the global fight against cancer.
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Expert Introduction
● Vice Chairman of the Oncology Emergency and Critical Care Committee of the Guangdong Provincial Chest Disease Association (First Term)
● Executive Member of the Lung Cancer Precision Treatment and Clinical Research Committee of the Guangdong Provincial Clinical Medicine Society
● Member of the Oncology Branch of the Guangdong Provincial Medical Association
● Member of the Radiotherapy Committee of the Guangdong Anti-Cancer Association
Specializes in: Precision radiotherapy for various tumors, comprehensive treatment of various neuro tumors and head and neck tumors, first in South China to carry out intrathecal chemotherapy for meningeal metastatic cancer, having completed over 5,000 cases of radiotherapy for brain metastases and various tumors, successfully rescuing over a hundred difficult and critical patients each year. Rich clinical experience in complex and difficult brain gliomas, pediatric neuro tumors, radiosurgery for brain metastases (CyberKnife, X-knife, Gamma Knife, etc.), comprehensive diagnosis and treatment of meningeal metastatic cancer, pituitary tumors, bone metastases, head and neck tumors.