JBC | Dentin Sialophosphoprotein (DSP) Acts as an Angiogenic Factor through Endoglin

JBC | Dentin Sialophosphoprotein (DSP) Acts as an Angiogenic Factor through Endoglin

Dentin sialophosphoprotein (DSPP) is highly expressed in odontoblasts responsible for dentin formation. Traditionally, DSPP is considered an extracellular matrix protein that regulates the formation and mineralization of dentin matrix. In Dspp knockout mice, in addition to defects in dentin formation, researchers observed a phenotype of reduced angiogenesis in certain regions of the femur. However, the … Read more