The “Connection Code” of Anti-Cancer ADCs: Unveiling the Advantages and Disadvantages of Three Coupling Technologies
Abstract: Antibody-drug conjugates (ADCs) represent a precise therapy for cancer, and their efficacy is closely related tocoupling technology. This article categorizes ADC coupling technologies from a popular science perspective intonon-specific, site-specific non-selective, and fully site-specific selective types, analyzing the characteristics, advantages, disadvantages, and clinical applications of mainstream technologies such as lysine coupling and cysteine coupling. … Read more