Differential Diagnosis of Tumor and Non-Tumor Lambert-Eaton Myasthenic Syndrome
Lambert-Eaton Myasthenic Syndrome (LEMS) is a disease affecting the neuromuscular junction, caused by the production of antibodies against voltage-gated calcium channels (VGCC) in the patient’s blood, leading to reduced acetylcholine release from the presynaptic membrane, resulting in specific clinical and electrophysiological manifestations. Approximately 50%-60% of LEMS patients have an associated tumor, classified as paraneoplastic syndrome … Read more
