CB-Dock2: An Improved Protein-Ligand Blind Docking Workflow Combining Homology Templates and FitDock Optimization
CB-Dock2 is an improved protein-ligand blind docking tool developed based on the original CB-Dock. Its workflow integrates three levels: traditional blind docking, homology template-assisted prediction, and fine-tuning optimization. First, it inherits the curvature-based pocket detection method from CB-Dock to identify surface pockets of the input protein and uses AutoDock Vina for initial blind docking, resulting … Read more